The National Laboratories undertake basic and applied research with special reference to the problems of industries falling within their spheres. These laboratories are actively associated with the work of industrial development and standardisation, each having its own detailed programme of work drawn up by expert committees.

● Birla Industrial and Technological Museum, Kolkata (West Bengal)
● Central Building Research Institute, Roorkee (Uttranchal)
● Central Drug Research Institute, Lucknow (Uttar Pradesh)
● Central Electro-Chemical Research Institute, Pilani (Rajasthan)
● Central Food Technological Research Institute, Mysore (Karnataka)
● Central Fuel Research Institute, Dhanbad (Jharkhand)
● Central Glass and Ceramic Research Institute, Kolkata (West Bengal)
● Central Institute of Medicinal and Aromatic Plants, Lucknow (Uttar Pradesh)
● Central Leather Research Institute, Chennai (Tamil Nadu)
● Central Mechanical Engineering Research Institute, Durgapur (West Bengal)
● Central Mining Research Station, Dhanbad (Jharkhand)
● Central Road Research Institute, New Delhi
● Central Salt and Marine Chemical Research Institute, Bhavnagar (Gujarat)
● Central Scientific Instruments Organisation, Chandigarh
● Indian Institute of Chemical Biology, Kolkata (West Bengal)
● Indian Institute of Petroleum, Dehradun (Uttaranchal)
● Industrial Toxicology Research Centre, Lucknow (Uttar Pradesh)
● National Aeronautical Laboratory, Bangalore (Karnataka)
● National Biological Laboratory (in Planning), Palampur, Kangra Distt. (Himachal Pradesh)
● National Botanical Research Institute, Lucknow (Uttar Pradesh)
● National Chemical Laboratory, Pune (Maharashtra)
● National Environment Engineering Institute, Nagpur
● National Geophysical Research Institute, Hyderabad (Andhra Pradesh)
● National Institute of Oceanography, Panaji (Goa)
● National Metallurgical Laboratory, Jamshedpur (Jharkhand)
● National Physical Laboratory, New Delhi
● Regional Research Laboratory, Bhubaneshwar (Odisha), Jorhat (Assam), Jammu (Jammu and Kashmir) and Hyderabad (Andhra Pradesh)
● Structural Engineering Research Centre, Roorkee (Uttaranchal) and Chennai (Tamil Nadu)
● Visvesvaraya Industrial and Technological Museum, Bangalore (Karnataka)